Kasséhin Urbain C. [1], Gbaguidi Fernand A. [2], McCurdy Christopher R. [3], Poupaert Jacques H. [4],
In a drug discovery program aimed at finding new anti-trypanosomal drugs, we developed the N, Ndimethylformamide.diiodine complex (DMF.I2) as an innov [...]
Article, Ajoutée le 17/01/2017 10:11
Gbaguidi A. Fernand [1], Kasséhin Urbain C. [2], Prevost Julien R. C. [3], Frederick Raphaël [4], McCurdy Christopher R. [5], Poupaert Jacques H. [6],
Relying on a straightforward « Green-Chemistry » based approach, this article reports an optimized Diels-Alder (DA) experimental set-up allowing for t [...]
Article, Ajoutée le 17/01/2017 10:25
Kasséhin Urbain C. [1], Gbaguidi A. Fernand [2], McCurdy Christopher R. [3], Poupaert Jacques H. [4],
Agomelatine, a melatonin-like antidepressant drug based on a naphthalene scaffold, has received considerable attention these last twenty years. This d [...]
Article, Ajoutée le 17/01/2017 10:32
Atchade Bardieu [1], KPOVIESSI DOSSOU SIKA SALOME [2], Gbaguidi A. Fernand [3], GLINMA BIENVENU [4], Ahoussi Léon A. [5], GBENOU Joachim [6], Accrombessi Georges C. [7], Frederick Raphaël [8], Poupaert Jacques H. [9],
Hydazones are molecules that inhibit the development of several microbes and parasites. They are known for their pharmacological activities: antimicro [...]
Article, Ajoutée le 17/01/2017 10:48
Kasséhin Urbain C. [1], Gbaguidi A. Fernand [2], McCurdy Christopher R. [3], Poupaert Jacques H. [4],
African trypanosomiasis remains a life-threatening disease and there is nowadays an urgent need for improved therapeutic agents for this pathology. In [...]
Article, Ajoutée le 17/01/2017 10:54
GLINMA BIENVENU [1], Gbaguidi A. Fernand [2], Kasséhin Urbain C. [3], KPOVIESSI Dossou Sika Salomé [4], Houngbeme Alban [5], Houngue Horrhus D. [6], Accrombessi Georges C. [7], Poupaert Jacques H. [8],
Hydrazones are nowadays considered to be good candidates for various pharmaceutical applications. Here, we have synthesized two series of hydrazones: [...]
Article, Ajoutée le 17/01/2017 11:06
Kasséhin Urbain C. [1], Gbaguidi A. Fernand [2], McCurdy Christopher R. [3], Poupaert Jacques H. [4],
Trypanosomiasis constitutes a severe health problem for sub-saharian African and latin American population and there is an urgent need for better drug [...]
Article, Ajoutée le 17/01/2017 11:37
Kasséhin Urbain C. [1], Gbaguidi A. Fernand [2], Kapanda Coco N. [3], McCurdy Christopher R. [4], Poupaert Jacques H. [5],
Article, Ajoutée le 17/01/2017 11:52
AGNIMONHAN Finagnon H. [1], AHOUSSI AKANNI LÉON [2], KPOVIESSI Dossou Sika Salomé [3], Gbaguidi A. Fernand [4], Kapanda Coco N. [5], MOUDACHIROU MANSOUROU [6], Poupaert Jacques H. [7], Accrombessi Georges C. [8],
Montmorillonite K-10 was used in the acid catalysis of the Willgerodt-Kindler’s reaction (WK) under microwave heating for synthesis of thiobenzamides. [...]
Article, Ajoutée le 17/01/2017 18:24
Kasséhin Urbain C. [1], Gbaguidi A. Fernand [2], Kapanda Coco N. [3], McCurdy Christopher R. [4], Poupaert Jacques H. [5],
This paper reports efforts aimed at tuning up the synthesis of a compound library centered on the general template 2amino-1-phenyl-2-thioxoethanonetak [...]
Article, Ajoutée le 18/01/2017 08:44