Kasséhin Urbain C. [1], Gbaguidi A. Fernand [2], Carato Pascal [3], McCurdy Christopher R. [4], Poupaert Jacques H. [5],
Based on a rational approach using merely bioisosterism as euristic tool, we designed and tested a short series of congeners of 6-benzoyl-2(3H)-benzox [...]
Article, Ajoutée le 18/01/2017 09:01
Kasséhin Urbain C. [1], Gbaguidi A. Fernand [2], Kapanda Coco N. [3], McCurdy Christopher R. [4], Bigot André K. [5], Poupaert Jacques H. [6],
A concise series of aldehydes and ketones were reacted in a condensation reaction with 4phenylthiosemicarbazide in order to assess the relative influe [...]
Article, Ajoutée le 18/01/2017 10:44
Poupaert Jacques H. [1], Gbaguidi A. Fernand [2], Kapanda Coco N. [3], Aichaoui Hocine [4], McCurdy Christopher R. [5],
Based on a line of evidence (logP, pKa, 1H-, and 13C-NMR, and molecular modeling studies), it appears that cocaine undergoes a hydrophobic collapse wh [...]
Article, Ajoutée le 19/01/2017 10:29
Fatondji Houssou Raymond [1], KPOVIESSI Dossou Sika Salomé [2], Gbaguidi A. Fernand [3], Bero Joanne [4], Hannaert Veronique [5], Quetin-Leclercq Joëlle [6], Poupaert Jacques H. [7], MOUDACHIROU MANSOUROU [8], ACCROMBESSI COFFI GEORGES [9],
To explore the structure–activity relationships of thiosemicarbazones on African trypanosome: Trypanosoma brucei brucei, a series of thirty-five thiose [...]
Article, Ajoutée le 19/01/2017 10:47
Sakirigui Amoussatou [1], KPOVIESSI Dossou Sika Salomé [2], Gbaguidi A. Fernand [3], Kossouoh Cosme [4], Bero Joanne [5], Quetin-Leclercq Joëlle [6], MANSOUROU Moudachirou [7], Poupaert Jacques H. [8], ACCROMBESSI COFFI GEORGES [9],
Extraction and analysis GC/FID and GC/MS showed that citral (neral + geranial) is the major compound of the essential oil of Benin Cymbopogoncitratus. [...]
Article, Ajoutée le 19/01/2017 11:05
Kasséhin Urbain C. [1], Gbaguidi A. Fernand [2], Carato Pascal [3], McCurdy Christopher R. [4], Accrombessi Georges C. [5], Poupaert Jacques H. [6],
A green synthesis of tetracyclone (2, 3, 4, 5-tetraphenyl-2, 4-cyclopentadien-1-one) has been conceived and executed on the basis of a rationale desig [...]
Article, Ajoutée le 25/01/2017 08:29
Gbaguidi A.Fernand [1], KPOVIESSI Salomé S. D. [2], Kapanda Coco N. [3], Muccioli Giulio G. [4], Lambert Didier M. [5], Accrombessi Georges C. [6], MOUDACHIROU MANSOUROU [7], Poupaert Jacques H. [8],
A reaction system is described to synthesize phenytoin, a major antiepileptic drug, and structurally related compounds using a two-step approach. The [...]
Article, Ajoutée le 26/01/2017 09:54
Gbaguidi A.Fernand [1], Kapanda Coco N. [2], Léon Ahoussi A. [3], Lambert Didier M. [4], Accrombessi Georges C. [5], MOUDACHIROU MANSOUROU [6], Poupaert Jacques H. [7],
The reaction of acenaphthone with morpholine and sulfur was studied in order to assess the effects of adding a source of acid or base in the Willgero [...]
Article, Ajoutée le 26/01/2017 10:34