Liste des Publications[ Poupaert Jacques H.]

Synthesis and antiepileptic activity assessment of 5-benzoyloxindole, a novel phenytoinergic template

Article, Ajoutée le 18/01/2017 09:01

Based on a rational approach using merely bioisosterism as euristic tool, we designed and tested a short series of congeners of 6-benzoyl-2(3H)-benzoxazolone as phenytoinergic lead. Among them, 5-benzoyloxindole showed an impressive activity in the M [...]

KASSÉHIN URBAIN C. [1], GBAGUIDI A. FERNAND [2], CARATO PASCAL [3], MCCURDY CHRISTOPHER R. [4], POUPAERT JACQUES H. [5],

Electronic and steric effects in the control of the anilinium chloride catalyzed condensation reaction between aldones and 4-phenylthiosemicarbazide

Article, Ajoutée le 18/01/2017 10:44

A concise series of aldehydes and ketones were reacted in a condensation reaction with 4phenylthiosemicarbazide in order to assess the relative influence of the steric and electronic effects in the control of this reaction. While steric effects had a [...]

KASSÉHIN URBAIN C. [1], GBAGUIDI A. FERNAND [2], KAPANDA COCO N. [3], MCCURDY CHRISTOPHER R. [4], BIGOT ANDRÉ K. [5], POUPAERT JACQUES H. [6],

Is cocaine a social drug? exploration of the stereo-structure of cocaine’s pharmacophore

Article, Ajoutée le 19/01/2017 10:29

Based on a line of evidence (logP, pKa, 1H-, and 13C-NMR, and molecular modeling studies), it appears that cocaine undergoes a hydrophobic collapse which may account for its unprecedented ADME properties, in particular, its exceptional capacity to cr [...]

POUPAERT JACQUES H. [1], GBAGUIDI A. FERNAND [2], KAPANDA COCO N. [3], AICHAOUI HOCINE [4], MCCURDY CHRISTOPHER R. [5],

Structure–activity relationship study of thiosemicarbazones on an african trypanosome: trypanosoma brucei brucei

Article, Ajoutée le 19/01/2017 10:47

To explore the structure–activity relationships of thiosemicarbazones on African trypanosome: Trypanosoma brucei brucei, a series of thirty-five thiosemicarbazones (1–35) have been synthesized and characterized by their 1H NMR, 13C NMR, and FT-IR spec [...]

FATONDJI HOUSSOU RAYMOND [1], KPOVIESSI DOSSOU SIKA SALOMÉ [2], GBAGUIDI A. FERNAND [3], BERO JOANNE [4], HANNAERT VERONIQUE [5], QUETIN-LECLERCQ JOËLLE [6], POUPAERT JACQUES H. [7], MOUDACHIROU MANSOUROU [8], ACCROMBESSI COFFI GEORGES [9],

Selective trypanocide activity of some substituted thiosemicarbazones of citral from benin cymbopogon citratus essential oil and their toxicity against artemia salina leach.

Article, Ajoutée le 19/01/2017 11:05

Extraction and analysis GC/FID and GC/MS showed that citral (neral + geranial) is the major compound of the essential oil of Benin Cymbopogoncitratus. This aldehyde was used as target for the hemi-synthesis in situ of the semicarbazone and substitute [...]

SAKIRIGUI AMOUSSATOU [1], KPOVIESSI DOSSOU SIKA SALOMÉ [2], GBAGUIDI A. FERNAND [3], KOSSOUOH COSME [4], BERO JOANNE [5], QUETIN-LECLERCQ JOËLLE [6], MANSOUROU MOUDACHIROU [7], POUPAERT JACQUES H. [8], ACCROMBESSI COFFI GEORGES [9],

Solid-liquid phase transfer catalysis and microwave-assisted green synthesis of tetracyclone

Article, Ajoutée le 25/01/2017 08:29

A green synthesis of tetracyclone (2, 3, 4, 5-tetraphenyl-2, 4-cyclopentadien-1-one) has been conceived and executed on the basis of a rationale design. Three separate, “green” processes to synthesize tetracyclone were undertaken to compare homogeneo [...]

KASSÉHIN URBAIN C. [1], GBAGUIDI A. FERNAND [2], CARATO PASCAL [3], MCCURDY CHRISTOPHER R. [4], ACCROMBESSI GEORGES C. [5], POUPAERT JACQUES H. [6],

A high yield synthesis of phenytoin and related compounds using microwave activation

Article, Ajoutée le 26/01/2017 09:54

A reaction system is described to synthesize phenytoin, a major antiepileptic drug, and structurally related compounds using a two-step approach. The first step involves the treatment of a benzil derivative by thiourea in dimethylsulfoxide (DMSO) i [...]

GBAGUIDI A.FERNAND [1], KPOVIESSI SALOMÉ S. D. [2], KAPANDA COCO N. [3], MUCCIOLI GIULIO G. [4], LAMBERT DIDIER M. [5], ACCROMBESSI GEORGES C. [6], MOUDACHIROU MANSOUROU [7], POUPAERT JACQUES H. [8],

General acid - base catalysis in the willgerodt-kindler reaction

Article, Ajoutée le 26/01/2017 10:34

The reaction of acenaphthone with morpholine and sulfur was studied in order to assess the effects of adding a source of acid or base in the Willgerodt-Kindler (WK) reaction. Addition of a strong acid was found beneficial particularly with Montmori [...]

GBAGUIDI A.FERNAND [1], KAPANDA COCO N. [2], LÉON AHOUSSI A. [3], LAMBERT DIDIER M. [4], ACCROMBESSI GEORGES C. [5], MOUDACHIROU MANSOUROU [6], POUPAERT JACQUES H. [7],

Publications par entité

  • Centre de Formation et de Recherche en matière de Population (CEFORP) (15)
  • Centre Interfacultaire de Formation et de Recherche en Environnement pour le Développement Durable (CIFRED) (18)
  • Chaire Internationale en Physique Mathématique et Applications (CIPMA-Chaire UNESCO) (16)
  • Ecole Nationale d'Administration et de Magistrature (ENAM) (44)
  • Ecole Nationle d'Economie Appliquée et de Management (72)
  • Ecole Normale Supérieure (23)
  • Ecole Polytechnique d'Abomey-Calavi (EPAC) (834)
  • Faculté de droit et de Science Politique (FADESP) (45)
  • Faculté des Lettres et Sciences Humaines (FLASH) (789)
  • Faculté des Sciences Agronomiques (1376)
  • Faculté des Sciences de la Santé (FSS) (1613)
  • Faculté des Sciences Economiques et de Gestion (FASEG) (136)
  • Faculté des Sciences et Techniques (FAST) (748)
  • Faculté des Sciences Humaines et Sociales (FASHS) (16)
  • Institut de Formation et de Recherche en Informatique (IFRI) (68)
  • Institut de Mathématiques et de Sciences Physiques (IMSP) (61)
  • Institut National de l'Eau (INE) (13)
  • INSTITUT NATIONAL DE LA JEUNESSE DE L’EDUCATION PHYSIQUE ET SPORT(INJEPS) (191)
  • Institut National des Métiers d'Art d'Archéologie et de la Culture (INMAAC) (4)
  • Institut Régional de Santé Publique (IRSP) (51)

Publications par sexe

  • Femme( 908 )
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