Liste des Publications[ Gbaguidi A. Fernand]

Insight into the diels-alder reaction: a green chemistry revisitation of the synthesis of a cantharidine-like trypanocidal pilot-molecule

Article, Ajoutée le 17/01/2017 10:25

Relying on a straightforward « Green-Chemistry » based approach, this article reports an optimized Diels-Alder (DA) experimental set-up allowing for this reaction to be cleanly operated in the presence of water used both as solvent and catalyst. Thi [...]

GBAGUIDI A. FERNAND [1], KASSÉHIN URBAIN C. [2], PREVOST JULIEN R. C. [3], FREDERICK RAPHAËL [4], MCCURDY CHRISTOPHER R. [5], POUPAERT JACQUES H. [6],

A concise synthesis of 2-(1,2,3,4-tetrahydro-6-methoxynaphthalen-4-yl) ethanamine, a key intermediate in the elaboration compound library of agomelatine analogs

Article, Ajoutée le 17/01/2017 10:32

Agomelatine, a melatonin-like antidepressant drug based on a naphthalene scaffold, has received considerable attention these last twenty years. This drug molecule undergoes important liver first pass effect and suffers therefore of a short plasma hal [...]

KASSÉHIN URBAIN C. [1], GBAGUIDI A. FERNAND [2], MCCURDY CHRISTOPHER R. [3], POUPAERT JACQUES H. [4],

Synthesis, characterization, purity verification, antiplasmodial activity and toxicity against artemia salina leach of salicylhydrazones and p-tosylhydrazones from s-(+)-carvone and arylketones

Article, Ajoutée le 17/01/2017 10:48

Hydazones are molecules that inhibit the development of several microbes and parasites. They are known for their pharmacological activities: antimicrobial, antiviral, antitumor, antimalarial, Anticonvulsant. In this research, we synthesized with good [...]

ATCHADE BARDIEU [1], KPOVIESSI DOSSOU SIKA SALOME [2], GBAGUIDI A. FERNAND [3], GLINMA BIENVENU [4], AHOUSSI LÉON A. [5], GBENOU JOACHIM [6], ACCROMBESSI GEORGES C. [7], FREDERICK RAPHAËL [8], POUPAERT JACQUES H. [9],

Synthesis and trypanocidal activity of salicylhydrazones and p-tosylhydrazones of s-(+)-carvone and arylketones on african trypanosomiasis

Article, Ajoutée le 17/01/2017 11:06

Hydrazones are nowadays considered to be good candidates for various pharmaceutical applications. Here, we have synthesized two series of hydrazones: salicylhydrazones (GS1-4) and p-tosylhydrazones (GT1-4) from S(+)-carvone and three aryketones with [...]

GLINMA BIENVENU [1], GBAGUIDI A. FERNAND [2], KASSÉHIN URBAIN C. [3], KPOVIESSI DOSSOU SIKA SALOMÉ [4], HOUNGBEME ALBAN [5], HOUNGUE HORRHUS D. [6], ACCROMBESSI GEORGES C. [7], POUPAERT JACQUES H. [8],

Synthesis of antitrypanosomal thiosemicarbazones using anthranilic acid as an innovative green nucleophilic catalyst

Article, Ajoutée le 17/01/2017 11:37

Trypanosomiasis constitutes a severe health problem for sub-saharian African and latin American population and there is an urgent need for better drugs to cure this life-threatening disease. In this context, aromatic thiosemicarbazones appears attrac [...]

KASSÉHIN URBAIN C. [1], GBAGUIDI A. FERNAND [2], MCCURDY CHRISTOPHER R. [3], POUPAERT JACQUES H. [4],

Comparative study of acid and basic catalysis in microwave assistance of willgerodt-kindler reaction for thiobenzamides and derivatives synthesis

Article, Ajoutée le 17/01/2017 18:24

Montmorillonite K-10 was used in the acid catalysis of the Willgerodt-Kindler’s reaction (WK) under microwave heating for synthesis of thiobenzamides. Yields of 67% and 43% for the synthesis of morpholin-4yl (phenyl) methanethione (1) and [4 - (dimet [...]

AGNIMONHAN FINAGNON H. [1], AHOUSSI AKANNI LÉON [2], KPOVIESSI DOSSOU SIKA SALOMÉ [3], GBAGUIDI A. FERNAND [4], KAPANDA COCO N. [5], MOUDACHIROU MANSOUROU [6], POUPAERT JACQUES H. [7], ACCROMBESSI GEORGES C. [8],

Synthesis and antiepileptic activity assessment of 5-benzoyloxindole, a novel phenytoinergic template

Article, Ajoutée le 18/01/2017 09:01

Based on a rational approach using merely bioisosterism as euristic tool, we designed and tested a short series of congeners of 6-benzoyl-2(3H)-benzoxazolone as phenytoinergic lead. Among them, 5-benzoyloxindole showed an impressive activity in the M [...]

KASSÉHIN URBAIN C. [1], GBAGUIDI A. FERNAND [2], CARATO PASCAL [3], MCCURDY CHRISTOPHER R. [4], POUPAERT JACQUES H. [5],

Trypanocidal and cytotoxic evaluation of synthesized thiosemicarbazones as potential drug leads against sleeping sickness

Article, Ajoutée le 18/01/2017 10:01

Thiosemicarbazones have become one of the promising compounds as new clinical candidates due to their wide spectrum of pharmaceutical activities. The wide range of their biological activities depends generally on their related aldehyde or ketone grou [...]

GLINMA BIENVENU [1], KPOVIESSI DOSSOU SIKA SALOMÉ [2], GBAGUIDI A. FERNAND [3], KAPANDA RENÉ MATHIAS [4], BERO JOANNE [5], QUETIN-LECLERCQ JOËLLE [6], MOUDACHIROU MANSOUROU [7], ACCROMBESSI COFFI GEORGES [8], GACHOMO EMMA W. [9], BABA-MOUSSA LAMINE [10], KOTCHONI SIMEON O. [11],

Publications par entité

  • Centre de Formation et de Recherche en matière de Population (CEFORP) (0)
  • Centre Interfacultaire de Formation et de Recherche en Environnement pour le Développement Durable (CIFRED) (0)
  • Chaire Internationale en Physique Mathématique et Applications (CIPMA-Chaire UNESCO) (0)
  • Ecole Nationale d'Administration et de Magistrature (ENAM) (0)
  • Ecole Nationle d'Economie Appliquée et de Management (0)
  • Ecole Normale Supérieure (0)
  • Ecole Polytechnique d'Abomey-Calavi (EPAC) (0)
  • Faculté de droit et de Science Politique (FADESP) (0)
  • Faculté des Lettres et Sciences Humaines (FLASH) (0)
  • Faculté des Sciences Agronomiques (0)
  • Faculté des Sciences de la Santé (FSS) (0)
  • Faculté des Sciences Economiques et de Gestion (FASEG) (0)
  • Faculté des Sciences et Techniques (FAST) (0)
  • Faculté des Sciences Humaines et Sociales (FASHS) (0)
  • Institut de Formation et de Recherche en Informatique (IFRI) (0)
  • Institut de Mathématiques et de Sciences Physiques (IMSP) (0)
  • Institut National de l'Eau (INE) (0)
  • INSTITUT NATIONAL DE LA JEUNESSE DE L’EDUCATION PHYSIQUE ET SPORT(INJEPS) (0)
  • Institut National des Métiers d'Art d'Archéologie et de la Culture (INMAAC) (0)
  • Institut Régional de Santé Publique (IRSP) (0)

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