Over the past century, research on cancer has increased due to the importance of the disease as sixth leading cause of mortality worldwide. Several medicines, methods and strategies have been used to cure the disease. However, the problematic of dr [...]
The quality control of medicines is one of the key factors which determine its efficacy. In Africa, particularly in Benin, a large population often uses traditional medicines. Therefore, controlling their quality becomes a major concern for public he [...]
Small size and high polar basic compounds have always been challenging with heavy matrix effect due to their difficult complete separation from polar endogenous compounds contained in most biological matrix. In this study, a relevant design including [...]
AGBOKPONTO JANVIER ENGELBERT [1], ASSANHOU ASSOGBA GABIN [3], DING LI [7],
Purpose: The aim of this study was to investigate the potential drug–drug interaction between Bencycloquidium bromide (BCQB) and paroxetine, and between BCQB and roxithromycin. Methods: Two studies were conducted on healthy male Chinese volunteers. [...]
Bencycloquidium bromide (BCQB) is a novel selective muscarinic M1/M3 receptor antagonist with potent therapeutic effects on rhinitis and chronic obstructive pulmonary disease. The metabolism of BCQB has been investigated in human liver microsomes [...]
Introduction: La quinine est une molécule préconisée pour le traitement du paludisme dans les régions où les souches de P. falciparum sont poly-résistantes. Face à l'importante utilisation de ses médicaments génériques d'une part et au fléau des médi [...]
KINDENGE MBINZE JEREMIE [1], DIALLO TIDIANE [2], YEMOA LOCONON Y. ACHILLE [3], HABYALIMANA VÉDASTE [4], WAFFO CHRISTELLE [5], HUBERT PHILIPPE [6], DJANG’EING’A MARINI ROLAND [6],
As one of the world’s most significant public health challenges in low- and middle-income countries,HIV/AIDS deserves to be treated with appropriate medicines, however which are not spared from coun-terfeiting. For that, we developed screening and sp [...]
HABYALIMANA VÉDASTE [1], KINDENGE MBINZE JEREMIE [2], YEMOA LOCONON Y. ACHILLE [3], WAFFO CHRISTELLE [4], KALENDA NICODÈME [5], NTOKAMUNDA JUSTIN-LÉONARD KADIMA [6], LEBRUN PIERRE [6], HUBERT PHILIPPE [6], DJANG’EING’A MARINI ROLAND [6],
But/objectif. – Évaluer la teneur en iode des sels de cuisine prélevés au sein des ménages de la commune de Glazoué (une zone surveillée pour endémie goitreuse), et l’état d’iodation du sel (supposé riche en iode) produit et commercialisé dans la co [...]
MIZÉHOUN-ADISSODA CARMELLE [1], AGUEH VICTOIRE DAMIENNE AGOSSI [2], YEMOA LOCONON Y. ACHILLE [3], ALIHONOU FLORENCE NATHALIE YACOBA [5], JOSSE ROGER GÉRARD [6], HOUINATO DISMAND STÉPHANE [7], BIGOT KOFFI ANDRÉ [8], DESPORT JEAN-CLAUDE [9],
Nowadays, the circulation of poor quality medicines is becoming an alarming worldwide phenomenon with serious public health and socio-economic concerns. The situation is particularly critical in developing countries where drug quality assurance and [...]
HABYALIMANA VÉDASTE [1], KINDENGE MBINZE JEREMIE [2], KALENDA NICODÈME [3], DISPAS ARMANDINE [4], YEMOA LOCONON Y. ACHILLE [5], SACRE PIERRE-YVES [6], ZIEMONS ERIC [11], DJANG’EING’A MARINI ROLAND [12],
Poor quality antimalarial drugs are one of the public’s major health problems in Africa. The depth of this problem may be explained in part by the lack of effective enforcement and the lack of efficient local drug analysis laboratories. To tackle p [...]
KINDENGE MBINZE JEREMIE [1], SACRE PIERRE-YVES [2], YEMOA LOCONON Y. ACHILLE [3], HABYALIMANA VÉDASTE [5], KALENDA NICODÈME [6], HUBERT PHILIPPE [7], ZIEMONS ERIC [8],