Breast cancer treatment is challenging due to the inconsistence in tumour biomarker expression including progesterone receptor (PR), estrogen receptor-α (ERα) and GATA3 transcription factor. GATA3 has role in epithelial cell differentiation along wit [...]
Background: Gastrointestinal stromal tumors are the most common mesenchymal tumors of the digestive tract with expression of phenotype KIT/CD117 and CD34+. The stomach and small intestine are the favored sites of occurrence. The most common complic [...]
Les gastrectomies partielles pour lésions bénignes peuvent se compliquer, plusieurs années après l’in-tervention, d’un cancer sur la portion restante de l’estomac. Nous rapportons ici un cas clinique d’adé-nocarcinome sur moignon de gastrectomie d’em [...]
GNANGNON FREDDY HOUEHANOU RODRIGUE [2], KPOSSOU ABOUDOU RAÏMY [1], LAWANI ISMAIL [4], VIGNON RODOLPHE KOFFI [5], SEHONOU J. [6],
Les tumeurs du sein sont fréquentes et surviennent à tout âge avec la hantise du cancer. Nous apportons notre contribution à leurs aspects diagnostiques et thérapeutiques chez les consultantes admises au C.HU-P (Bénin). Patientes et Méthodes : li s [...]
MENSAH EMILE [1], SAVI DE TOVE S. [2], KOUDOUKPO C, [3], BRUN LUC V. C. [4], HODONOU M. A. [5], TAMOU B. E. [6], GODJO E. [6], ALLODE A. [6], AKELE-AKPO MARIE THÉRÈSE [6],
A small proportion of women who are exposed to infection with human-papillomavirus (HPV) develop cervical cancer (CC). Genetic factors may affect the risk of progression from HPV infection to cervical precancer and cancer. We used samples from the In [...]
MCKAY JAMES [1], TENET VANESSA [2], FRANCESCHI SILVIA [3], CHABRIER AME ́LIE [4], GHEIT TARIK [5], GABORIEAU VALERIE [6],
Circulating tumor DNA (ctDNA) is emerging as a key potential biomarker for post-diagnosis surveillance but it may also play a crucial role in the detection of pre-clinical cancer. Small-cell lung cancer (SCLC) is an excellent candidate for early dete [...]
FERNANDEZ-CUESTA LYNNETTE [1], PERDOMO SANDRA [1], AVOGBE HODONOU PATRICE [1], LEBLAY NOEMIE [4], DELHOMME TIFFANY [5], GABORIEAU VALERIE [6],
The use of non-invasive biomarkers such as circulating tumor DNA (ctDNA) in head and neck tumors may be of relevance in early diagnosis and eventually improved outcome. We evaluated two different approaches from two case series in Europe and South Am [...]
PERDOMO SANDRA [1], AVOGBE HODONOU PATRICE [1], FOLL MATTHIEU [3], ABEDI-ARDEKANI BEHNOUSH [4], VIOLETA LESCHER FACCIOLLA [5], ANANTHARAMAN DEVASENA [6],
The molecular mechanisms of hepatocellular carcinoma (HCC) carcinogenesis are still not fully understood. DNA repair defects may in uence HCC risk. The aim of the study was to look for potential genetic variants of DNA repair genes associated with HC [...]
OUSSALAH ABDERRAHIM [1], AVOGBE HODONOU PATRICE [1], GUYOT ERWAN [3], CHERY CÉLINE [4], GUÉANT-RODRIGUEZ ROSA-MARIA [5], GANNE-CARRIÉ NATHALIE [6],
BACKGROUND: Few data exist concerning familial human T-cell leukaemia virus type I (HTLV-I) carrier states and transmission in African countries. Two previous surveys performed in Benin in 1989 and 1990 using a three-level cluster sampling method all [...]
HOUINATO DISMAND [1], VERDIER M. [2], PREUX P. M. [3], JOSSE R. [4], LETENNEUR L. [5], AYED Z. [6], AVODÉ G. [7], MASSIT B. [8], BOUTROS-TONI F. [9], DENIS F. [10], ZOHOUN T. [11], SALAMON R. [12],
Abstract BACKGROUND: High risk oncologic Human Papilloma Virus (HPV) is one of the leading causes of cervical cancer worldwide. We investigated HPV genotypes among women living or not with Human Immuno-deficiency Virus (HIV) in two major hospitals [...]
CAPO-CHICHI D. CALLINICE [1], AGUIDA BLANCHE [2], CHABI NICODEME [3], ACAPKO-EZIN JOCELYN [4], SOSSAH-HIFFO JONAS [1], AGOSSOU VIDEHOUENOU KOMLAN [6], ANAGBLA TOUSSAIN [7], ZANNOU MARCEL [8], HOUNGBE FABIEN [9], SANNI AMBALIOU [10],