Liste des Publications[Pharmacie, Pharmacologie & Toxicologie]

Antihypertensive effects of moringa oleifera leaf extract lam. (moringaceae) in ng-nitro-l-arginine-methyl ester-induced hypertensive rats

Article, Ajoutée le 18/03/2021 15:45

The use of natural products such as Moringa oleifera (MO) for the improvement of resistance artery relaxation is a potential strategy for the prevention and treatment of hypertension. Aims and Objective: The present study was desig [...]

GBANKOTO ADAM [1], SINDETE MARIETTE [2], ADJAGBA MARIUS [3], SANGAR MAXIME MACHIOUD [4], ATTAKPA S. EUGÈNE [5], AWEDE BONAVENTURE L. SÉVERIN [6],

A phase ii pilot trial to evaluate cobat-y017 safety and efficacy against uncomplicated falciparum malaria versus artemether-lumefantrine in benin subjects

Article, Ajoutée le 05/03/2021 18:45

Background: Considering the promising results of Phase I clinical trials with herbal medicine CoBaT-Y017, a Phase II study was conducted with Plasmodium falciparum malaria-infected patients, for efficacy and safety evaluation of CoBaT-Y017, a Phase I [...]

ALLABI AUREL C. E. [6], NOUDJIEGBE ADRIEN N. [1],

A prospective analysis of potential and observed drug-drug interactions, adverse events and its associated risk factors in hospitalized cardiology patients in benin

Article, Ajoutée le 05/03/2021 18:29

Background & aims: The objective is to ascertain the pattern of potential drug-drug interactions (pDDIs) and record any observed DDIs and adverse events (AEs) in hospitalized Beninese cardiology patients from Sub-Saharan Africa and analyze all risk f [...]

ALLABI AUREL C E [1], YESSOUFOU CHABI YESSOUFOU CHABI [2],

Short-term safety and tolerability of an antimalarial herbal medicine, cobat-y017 in healthy volunteers.

Article, Ajoutée le 05/03/2021 18:17

Background: Malaria is the most prevalent parasitic disease in Benin and the main cause of morbidity and mortality. To fight this disease, a large proportion of the population resorts to herbal drugs. However, for most of these herbal preparations, n [...]

NOUDJIEGBE ADRIEN N. [1], GNIMASSOU ADELINE L. [2], GBENOUDON J. [3], DEGBELO JEAN EUDE [4], ALLABI AUREL C. E. [5],

Peroxisome proliferator-activated receptor-α gene modulates insulin transcriptional factors and inflammation in adipose tissues mice.

Article, Ajoutée le 17/02/2021 17:09

We have recently reported that PPARa deficiency leads to hypoglycaemia and hypoinsulinemia in mice (Yessoufou et al. Endocrinology 147:4410–4418, 2006). Besides, these mice exhibited high adiposity with an inflammatory state. We, therefore, asses [...]

YESSOUFOU AKADIRI [1], ATÈGBO JEAN-MARC. [2], ATTAKPA SÈLIDJI EUGÈNE [3], HICHAMI AZIZ [4], MOUTAIROU KABIROU [5], DRAMANE KARIM [6], KHAN NAIM [6],

Protective effects of boerhavia diffusa linn. (nictaginaceae) on liver of streptozotocin-induced

Article, Ajoutée le 17/02/2021 17:07

The aim of this study was to evaluate the hepatoprotective of Boerhavia diffusa Linn. used in Benin and other countries to manage control and treat diabetes. Streptozotocin (STZ) is selectively toxic to cells in the pancreatic islets. It is well know [...]

MAMA SIROU AMIDOU IBRAHIMA [1], ATTAKPA SÈLIDJI EUGÈNE [2], AKOTEGNON RODRIGUE [3], AMOUSSA ABDOU MADJID [4], GUINNIN FÉLIX [5], LAGNIKA LATIFOU [6],

The effect of methanolic leaf extract of boerhaviadiffusa linn. (nictaginaceae) on the activities of antidiabetic,anti-inflammatory and antioxidant enzymes in experimental diabetes.

Article, Ajoutée le 17/02/2021 17:06

Diabetic therapeutic potentiality of methanol extract of stem leaves of Boerhavia diffusa was investigated following in-vivo study models in streptozotocin-induced diabetic rat. Methanol extract of stem leaves of Boerhavia diffusa exerted the gluco [...]

MAMA SIROU AMIDOU IBRAHIMA [1], ATTAKPA SÈLIDJI EUGÈNE [2], BEHANZIN GBÉSSOHÈLÈ JUSTIN [3], AMOUSSA ABDOU MADJID, [4], SANGARÉ MAXIME MACHIOUD [5], AKOTEGNON RODRIGUE [6],

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