Liste des Publications[ Laboratoire de Biochimie et de Biologie Moléculaire (LBBM)]

La perte de la protéine brca1 dans les cellules cancéreuses mammaires issues des micro-biopsies au bénin.

Communication, Ajoutée le 22/01/2021 12:58

Résumé : La protéine BRCA1 (breast cancer 1) est un suppresseur de tumeur impliqué dans les fonctions cellulaires de base nécessaires à la réplication cellulaire et à la synthèse de l'ADN, mais une expression réduite de BRCA1, due à des mutations ou [...]

Sara HOUNGUE [1], Fréddy GNANGNON [2], Callinice D. Capo-chichi [1], Sophia George [3], Xiang-Xi Xu [3]. 1. FAST/ISBA/ Université d’Abomey Calavi, 2. CNHU-HKM Cotonou, 3. Sylvester Cancer Center/ Université de Miami, USA.

High risk hpv genotypes in the south of benin and lack of association with cervical dysplasia: a decade investigation

Communication, Ajoutée le 22/01/2021 12:36

ACT Introduction: High Risk Oncogenic Human Papillomavirus (HR-HPV) are accountable for 7.7% of cancers in developing countries, mainly cervical cancer. In Benin, HR-HPV infection in women triggered nearly 781 new cases of cervical cancer each year [...]

Marie-Marthe A. Chabi [1,2], *Callinice D. Capo-chichi [1,2], Théodora M. Zohoncon [3], Christine Aguemon [4], Ambaliou Sanni [1,2], Jacques Simporé [3]. 1. Unit of Biochemistry and Molecular Biology (UBBM), Division of Molecular Biomarker in Cancer and Nutrition (BMCN), Department of Biochemistry and cell Biology, Faculty of Sciences and Technics (FAST), University of Abomey Calavi (UAC), Cotonou, Benin. 2. Institute of Biomedical Sciences and Applications (ISBA). 3. “Pietro Annigoni Center for Biomolecular Research CERBA, laboratory of Molecular Biology and Genetic (LABIOGENE), University of Ouagadougou, 01BP364 Ouagadougou 01, Burkina Faso. 4. Division of Gynecology/obstetrics, National University Hospital (CNHU-HKM), Cotonou, Benin

Communication: histone deacetylase inhibitor induced downregulation of gata3 and er-αlpha in breast cancer cells expressing lamin a

Communication, Ajoutée le 22/01/2021 12:27

Background: Breast cancer treatment is challenging due to the inconsistence in tumour biomarker expression including progesterone receptor (PR), estrogen receptor-α (ERα) and GATA3 transcription factor. GATA3 has role in epithelial cell differentiati [...]

Callinice D. Capo-chichi [1,3],*, Freddy Gnangnon [2], Charles Mekpossi [1], Sara Houngue1, Xiang-Xi Xu [3], Jean-Leon Olory-Togbé [2 1]. Institute of Biomedical Sciences and Applications (ISBA), Division of Molecular Biomarkers in Cancer and Nutrition (BMCN), Department of Biochemistry and Cell biology, Faculty of Sciences and Technology (FAST), University of Abomey-Calavi (UAC). 2. Visceral Surgery, National University Hospital (CNHU-HKM), School of Medicine, University of Abomey-Calavi (UAC). 3. Sylvester Comprehensive Cancer Center, Miller Medical School, University of Miami *Corresponding author: callinice.capochichi@fast.uac.bj

Molecular mechanisms underlying brca1 deficiency may determine personalized targeted therapy and overall survivor of patient with cancer in benin

Communication, Ajoutée le 22/01/2021 11:29

Molecular mechanism underlying BRCA1 deficiency may determine personalized targeted therapy and overall survivor of patient with breast in Benin. Callinice D. Capo-chichi1***, Sara Houngue 1, Fréddy Gnangnon2, Sophia George3, Xiang-Xi Xu3, Jean-L [...]

Callinice D. Capo-chichi, PhD, MPH* ; Sara Houngue, MS ; Fréddy Gnangnon, MD ; Sophia George, PhD; Xiang-Xi Xu, PhD; Jean-Léon Olory-Togbé, MD.

Molecular mechanism underlying brca1 deficiency may determine cancer in benin

Poster, Ajoutée le 21/01/2021 17:36

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Callinice D. Capo-chichi [1]***, Sara Houngue [1], FréddyGnangnon [2], Sophia George [3], Xiang-Xi Xu [3], Jean-Leon Olory-Togbé [2]. 1. CD; SH: Department of Biochemistry and Cell Biology, FAST/ISBA/ University of Abomey Calavi, Cotonou, Benin. 2. FD; JO: Department of Visceral surgery, National University hospital (CNHU-HKM) Cotonou, Benin. 3. SG; XX. Departementsof gynecology and Cell Biology; Sylvester Cancer Center/ Université de Miami, USA. CAPO-CHICHI D. CALLINICE [1], HOUNGUE SARA [2], GNANGNON FREDDY [3], GEORGE SOPHIA [4],