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[ Article ] Phytochemical analysis, toxicity and larvicidal activity of extracts from Launaea taraxacifolia (Asteraceae) on Anopheles gambiae, a malaria vector

Date de soumission: 20-01-2017
Année de Publication: 2016
Entité/Laboratoire Autres laboratoires
Document type : Article
Discipline(s) : Chimie
Titre Phytochemical analysis, toxicity and larvicidal activity of extracts from Launaea taraxacifolia (Asteraceae) on Anopheles gambiae, a malaria vector
Auteurs Ahouansou C. Ayidé [1], Fagbohoun Louis [2], Medegan Fagla Sèdami R. [3], Tchetche Jules [4], KOTCHONI SIMEON [5], Gbagudi A. Fernand [6],
Journal: International Journal of Vector Borne Diseases
Catégorie Journal: Internationale
Impact factor: 0
Volume Journal: 107
Resume In the search for alternative methods to chemical control, the use of bio-insecticides is increasingly developed against mosquitoes, vectors of disease. The extracts of native plants are very promising in this new perspective. This work aims to determine the efficacy of extracts Launaea taraxacifolia larvicidal agent as well as its possible use in the control of malaria vectors. To do this, extracts of L. taraxacifolia were tested on the larvae (third stage) of Anopheles gambiae Kisumu and wild strains, as well as the larvae of shrimp Artemia salina. It shows that the hydro-methanol extract was the most active with lethal concentrations LC50 of 469.7 ppm and 12.2 ppm in 24 and 48 h of exposure for strain Kisumu; 270.7 ppm and 166.7 ppm in 24 h and 48 h, respectively, for the wild population. Strong lethal doses (LC50 > 2668 ppm) extracts on larvae of Artemia salina, denote their innocuousness on shrimp. Thus, L. taraxacifolia is a good candidate for the development of a bio-larvicide agent for the integrated fight against malaria vectors and the differential activity of its extracts on larvae is due to secondary metabolisms they contain and that it will specifically identify later.
Mots clés Anopheles gambiae; Artemia salina; Launaea taraxacifolia; larval toxicity; Malaria, Benin
Pages 130 - 138
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