Publications Scientifiques

[ Article ] Evaluation of the phytochemical and hemostatic potential of Jatropha multifida sap

Date de soumission: 23-01-2017
Année de Publication: 2012
Entité/Laboratoire Laboratoires de Chimie Organique Phisyque et de Synthèse (LRCOPS)
Document type : Article
Discipline(s) : Chimie
Titre Evaluation of the phytochemical and hemostatic potential of Jatropha multifida sap
Auteurs Dougnon Tamègnon Victorien [1], Klotoé Jean Robert [2], Sègbo Julien [3], Atègbo Jean-Marc [4], Edorh Aléodjrodo Patrick [5], Gbaguidi A. Fernand [6], Hounkpatin Armelle Sabine [7], DANDJESSO Carlos [8], Fah Lauris [9], Brice Fanou [10], Dramane Karim [11], LOKO Frédéric [12],
Journal: African Journal of Pharmacy and Pharmacology
Catégorie Journal: Internationale
Impact factor: 0.839
Volume Journal: 6
DOI:
Resume Jatropha multifida is a plant traditionally recognized for its medicinal properties. This study was undertaken not only to assess the hemostatic potential of the sap of J. multifida, but also to elucidate its chemical profile. Wistar rats were injured at various locations and time of bleeding was evaluated based on the addition of J. multifida’s sap or distilled water. Phytochemical study was performed on sap. J. multifida’s sap significantly reduced bleeding time. Indeed, more blood flow was noticed on the side that received physiological water than the one which received the sap. This is even truer when the cut is deep with times of bleeding reduction of 39.06, 47.89, and 46.68%, respectively for superficial wounds, saphenous vein, and the femoral vein clippings. The phytochemical screening of J. multifida showed the presence of tannins, flavonoids, saponins, leucoanthocyanes, mucilage and reducing compounds. The power of the hemostatic sap is explained by the strong presence of tannins and flavonoids. All this proves that using the sap of J. multifida in traditional medicine is justified.
Mots clés Hemostatic, Wistar rats, tannins, flavonoids, bleeding, Jatropha multifida
Pages 1943 - 1948
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