||Moringa oleifera leaf powder (MOLP) was incorporated into patient diets in order to study its effects
on the levels of fasting blood glucose (FBG), glycated haemoglobin (HbA1c), serum triglyceride
(TG), total cholesterol (TC), high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL)
cholesterol, and body weight (BW) in those at the early stages of Type 2 diabetes mellitus (T2DM).
Two tablespoons (20 g) of the leaf powder were added to a basic diet of food served cold daily at lunch
and dinner for a period of 3 months. Pre-diabetic control subjects were given the basic diet without
MOLP. The supplementation of MOLP into the basic diet significantly (p<0.05) reduced the elevated
FBG, HbA1c, TG, TC, and LDL cholesterol levels in the MOLP-diet group, while an increase in HDL
cholesterol was also recorded. MOLP exerted more pronounced effects at the end of the study when
compared with the control group. Overall, BW was reduced, with better results recorded in the MOLP
group. Considering the changes when compared to each initial value, the efficacy of the MOLP diet on
biochemical parameters was 3.55–24.79% greater. The introduction of the effective potential change
revealed an efficacy induction of 8.85–36.83% due to the MOLP diet, with a relative performance
factor ranging from 1.50–4.85 among the biochemical parameters. The findings suggest that MOLP
possesses promising anti-hyperglycaemic, anti-hyperlipidaemic, and lipid profile regulatory properties
in T2DM subjects.