Publications Scientifiques

[ Article ] Phytochemical Profile and Antioxidant Potential of 12 Antimalarial Recipes Used in Lacustrine Areas In Benin

Date de soumission: 09-02-2017
Année de Publication: 2016
Entité/Laboratoire Laboratoire d'Etude et de Recherche en Chimie Appliquée (LERCA)
Document type : Article
Discipline(s) : Chimie
Titre Phytochemical Profile and Antioxidant Potential of 12 Antimalarial Recipes Used in Lacustrine Areas In Benin
Auteurs Medoatinsa Seindé E. [1], AGBANGNAN DOSSA COKOU PASCAL [2], BOGNINOU AGBIDINOUKOUN G. SOPHIE REINE [3], AHISSOU HYACINTHE [4], BOTHON FIFA THEOMAINE DIANE [5], WOTTO VALENTIN DIEUDONNÉ [6], AVLESSI FÉLICIEN [7], SOHOUNHLOUE KOKO CODJO DOMINIQUE [8],
Journal: International Journal of Pharmaceutical Science Invention
Catégorie Journal: Internationale
Impact factor: 0
Volume Journal: 5
DOI:
Resume The present work aims to identify the major chemical groups and to evaluate the anti-radical activity of 12 recipes of medicinal plants used in the treatment of malaria among children, pregnant women and adults in two lake villages (Ganvi , Aguegues Daho) of southern Benin. All the recipes contain molecules able to trap the 2,2-diphenyl-1-picrylhydrazyl (DPPH) which is a free radical. This activity would be due to the phenolic compounds identified in the phytochemical screening and whose presence in these recipes has been confirmed by quantitative test performed in a spectrophotometer. Aqueous extract obtain by decoction of recipes 3, 1 and 4 (E3, E1, E4) of the child have the higher contents of total phenolics compounds and good anti-radical activity compared to other extracts. The aqueous extract obtain by decoction of the recipe 3 which has the strongest content of total polyphenols (668.16 mg EAG/g DM) was the most active for trapping DPPH with an IC50 of 0.095 mg/mL similar to those of butylated hydroxyanisole (0.090 mg/mL) and quercetin (0.100 mg/mL) that are reference antioxidants used in this study. These results justify the use of these traditional recipes.
Mots clés Malaria, plants, phenolic compound, DPPH
Pages 16 - 21
Fichier

Publications par entité

  • Centre de Formation et de Recherche en matière de Population (CEFORP) (15)
  • Centre Interfacultaire de Formation et de Recherche en Environnement pour le Développement Durable (CIFRED) (18)
  • Chaire Internationale en Physique Mathématique et Applications (CIPMA-Chaire UNESCO) (16)
  • Ecole Nationale d'Administration et de Magistrature (ENAM) (46)
  • Ecole Nationle d'Economie Appliquée et de Management (73)
  • Ecole Normale Supérieure (23)
  • Ecole Polytechnique d'Abomey-Calavi (EPAC) (860)
  • Faculté de droit et de Science Politique (FADESP) (47)
  • Faculté des Lettres et Sciences Humaines (FLASH) (825)
  • Faculté des Sciences Agronomiques (1387)
  • Faculté des Sciences de la Santé (FSS) (1668)
  • Faculté des Sciences Economiques et de Gestion (FASEG) (137)
  • Faculté des Sciences et Techniques (FAST) (757)
  • Faculté des Sciences Humaines et Sociales (FASHS) (18)
  • Institut de Formation et de Recherche en Informatique (IFRI) (69)
  • Institut de Mathématiques et de Sciences Physiques (IMSP) (62)
  • Institut National de l'Eau (INE) (13)
  • INSTITUT NATIONAL DE LA JEUNESSE DE L’EDUCATION PHYSIQUE ET SPORT(INJEPS) (191)
  • Institut National des Métiers d'Art d'Archéologie et de la Culture (INMAAC) (4)
  • Institut Régional de Santé Publique (IRSP) (51)

Publications par sexe

  • Femme( 939 )
  • Homme (