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[ Article ] Factors associated with dementia among elderly people living in two cities in Central Africa: the EDAC multicenter study

Date de soumission: 23-02-2017
Année de Publication: 2012
Entité/Laboratoire Laboratoire Épidémiologisque des Maladies Chroniques et Neurologiques (LEMACEN)
Document type : Article
Discipline(s) : Neurologie
Titre Factors associated with dementia among elderly people living in two cities in Central Africa: the EDAC multicenter study
Auteurs Guerchet M. [1], Mouanga Alain M. [2], M'belesso Pascal [3], Tabo André [4], Bandzouzi Bébène [5], PARAÏSO NOEL MOUSSILIOU [6], Houinato Dismand [7], Cowppli-Bony Pascale [8], Nubukpo Philippe [9], Aboyans Victor [10], Clément Jean-Pierre [12], Dartigues Jean-François [12],
Journal: Journal of Alzheimer's disease: JAD
Catégorie Journal: Internationale
Impact factor: 0
Volume Journal: 29
DOI: 10.3233/JAD-2011-111364
Resume Risk factors for dementia in American and European countries have been well investigated. However, little research has been carried out in sub-Saharan Africa, where life events as well as environmental, socio-economic, and modifiable risk factors (i.e., cardiovascular risk factors) may differ. Two cross-sectional surveys were conducted in representative samples of the older general population living in Bangui (Central African Republic) and Brazzaville (Congo). Dementia was defined according to the DSM-IV criteria. Multivariate regression analyses were performed in order to identify independent factors associated with dementia. Among the 977 elderly Africans included in this analysis, 75 (7.6%) were diagnosed as having dementia. Increasing age, female gender, hypertension, a body mass index <18.5 kg/m2, depressive symptoms, and the lack of a primary education were significantly associated with dementia. Among life events, the death of one parent during childhood and recently having moved house were also associated with dementia. Beyond the usual risk factors for dementia, this study highlights the role of stressful events in low-income countries. Factors associated with dementia in African countries seem different from established factors in high-income countries and require further investigation.
Mots clés Factors associated, dementia
Pages 15 - 24
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