Titre |
Post-Stroke Cognitive Disorders and Associated Factors in French Speaking West Africa, Benin Case |
Auteurs |
GNONLONFOUN DIEU-DONNÉ [1],
Ossou-Nguiet Paul Macaire [2],
DIALLO B.O. [3],
ADJIEN KODJO CONSTANT [4],
Avlessi Isaac [5],
Goudjinou Gérald [6],
Houannou Octave [7],
Houinato Dismand [7],
AVODE DOSSOU GILBERT [9],
|
Journal: |
Neuroscience and Medicine |
Catégorie Journal: |
Nationale |
Impact factor: |
0 |
Volume Journal: |
5 |
DOI: |
10.4236/nm.2014.51006 |
Resume |
Introduction: Cognitive disorders frequency arising after a cardio-cerebral vascular disease (stroke) is currently on the rise due to the ageing population and the increase in the number of survivors after stroke occurrence. Objective: Determining post-stroke cognitive decline and identifying associated factors. Method: It consists in a cross-sectional, prospective, descriptive and analytical study which was conducted from April 1 to August 31, 2013 in the Neurology Department of CNHU-HKM in Cotonou. The study involved 100 patients who have known stroke for at least the past 6 months and were all admitted and discharged later on. The disease survivors were re-contacted and examined again at home or at hospital. The cognitive decline (CD) was estimated by using a modified and adapted MMSE to suit our cultural era. Results: All patients were aged 58.9 years ± 13.6 years. Sex-ratio was 1.4. Cognitive decline frequency was 20%. Post-stroke cognitive decline frequency per sex was 11.6% and 8.4% respectively for females and males. Ischemia stroke patients had a higher cognitive decline (22.5%). 58.3% had severe CD. Moreover the CD frequency increased with time, from 16.7% in a year to 50% in 3 years. Total MMSE varied from 6 to 23 with 21 as median. From the unvaried analysis, the presence of sphincter disorders (1.26 [0.35-4.59], p = 0.004), consciousness disorders (15.67 [1.46-168], p = 0.04), and convulsion disorders (3.77 [1.01 -14.00], p = 0.003) was associated with cognitive decline. From multi-varied analysis, the sole presence of convulsive attacks (11.5 [1.79-73.58], p = 0.01) was individually associated with post-stroke cognitive decline. Conclusion: This study reveals the importance of CD after stroke. The occurrence of convulsions at stroke acute stage is a prognostic factor of CD medium or long-term occurrence. The overall coverage improvement depends on the integration of these data in stroke reach-out programs. |
Mots clés |
Post-Stroke, Cognitive Disorders, Associated Factors |
Pages |
1 - 32 |
Fichier |
(PDF) |