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[ Article ] Epidemiological, Clinical, Biological, Therapeutic Features and Outcome of Congenital Malaria at the Borgou Regional University Teaching Hospital (CHUD-B) in Benin in 2015

Date de soumission: 24-02-2018
Année de Publication: 2017
Entité/Laboratoire Unité de Pédiatrie et Génétique Médicale/Hosp (UPGM)
Document type : Article
Discipline(s) : Pédiatrie
Titre Epidemiological, Clinical, Biological, Therapeutic Features and Outcome of Congenital Malaria at the Borgou Regional University Teaching Hospital (CHUD-B) in Benin in 2015
Auteurs SAGBO GODONOU GRATIEN [1], Noudamadjo Alphonse [2], AGOSSOU JOSEPH [3], Adedemy Julien Didier [4],
Journal: Open Journal of Pediatrics
Catégorie Journal: Internationale
Impact factor: 0.44
Volume Journal: 7
DOI: DOI: 10.4236/ojped.2017.74030
Resume Background: The prevalence of congenital malaria is getting more and more significant in Sub-Saharan Africa where is a malaria-endemic area. This study aimed to identify the clinical and therapeutic features as well as the outcome of congenital malaria in CHUD-B in 2015. Method: It was a cohort and descriptive study with analytical purpose, carried out in the Mother and Child Department which includes the Gynecology & Obstetrics and Pediatric Unit of CHUD-B. The study target population consisted of all the infants born in the CHUD-B as well as their mothers. The main variable was the presence of congenital malaria. The independent variables were those related to clinical, therapeutic features and outcome. Results: In the study, among the 300 newborns registered, 57 carried congenital malaria i.e. a prevalence of 19%. 171 (57.0%) of them were males versus 129 (43.0%) females. Among the 281 mothers involved, 48 presented with malaria in pregnancy i.e. a prevalence of 17.0%. At the end of this research work, the factors associated with congenital malaria were fever in the 3rd quarter and malaria in pregnancy in the mother. Conclusion: Nearly one out of five infants born in the CHUD-B was carrier of congenital malaria and approximately one out six mothers presented with malaria detection during pregnancy. A method based on Polymerase Chain Reaction (PCR) should be implemented during the diagnosis in order to confirm malaria cases among both newborns and mothers
Mots clés Congenital Malaria, Outcome, Benin
Pages 263 - 271
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