||Serratia Marcescens outbreak on a general pediatric ward in Benin
AHOYO THEODORA ANGÈLE ,
BABA MOUSSA Faride ,
ADEOTI MANSOUR ,
BABA MOUSSA Lamine ,
||Research Journal of Pharmaceutical Sciences
||ISSN NO- 2230 – 7885
: Increasing reports in the literature document the existence of nosocomial transmission of
The consequences of infections associated to this bacterium can be severe, so it was
important to establish strategies for prevention. This study aimed to provide the prevalence of this
bacterium in a hospital environment and to examine the main factors increasing the risk of cross contamination.
Methods: Various specimen obtained from 790 hospitalized children aged from 0 to 7 years were
examined and 940 others samples taken from hands of medical personnel, and various hospital surfaces
were also screened for Serratia marcescens presence. Susceptibilities to antimicrobial agents were tested
by the disk diffusion method according to NCCLS guidelines. Aggressive infection control measures were
Results: About 123 (38%) patients were infected by Serratia marcescens, including septicaemia 65
(52.85%), 31 (25.2%) urinary tract infections, 12 (9.75%) pneumonia and 15 (12.2%) others
infections. From hospital environment, 108/940 (11.50%) isolates were obtained. Antimicrobial
susceptibility testing revealed that 56% of strains displaying multi resistance. Infected patients were
cohorted and placed on contact precautions. Investigation by the infection control team revealed that the
distributors of antiseptic were the main path of Serratia marcescens dissemination.
Conclusions: A substantial proportion of cases appeared to be of medical devices origin. New infection
control policies and engineering plans were initiated on the basis of our results. Antimicrobial resistance
is particularly harmful to infectious disease management in low-income countries since expensive
second-line drugs are not readily available.
||Benin, Nosocomial infection, prevention, pediatrics unit, Serratia marcescens.
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