||Acanthosis Nigricans during an HAIR-AN syndrome: "The Tree That Hides the Forest"
GNINKOUN COMLAN JULES ,
DEGBOE BÉRÉNICE ,
||Journal of Clinical & Experimental Dermatology Research
||Introduction: Acanthosis nigricans is broadly classified into malignant and benign forms. Recent attention has
been directed toward its benign endocrine associations. Acanthosis nigricans is a significant marker for insulin
Observation: A 20-years-old girl has consulted for macular, hyperpigmented, papillomatic lesions which were on
the neck with overflows on the mandibular areas and the ears, in the vertebral groove, the armpits, and the umbilicus. These lesions were associated with a clinical syndrome of hyperandrogenism. The blood sample showed hyperglycemia at 1.3 g/dl, hyperprogesteronemia at 0.63 ng/mL, hypertestosteronemia at 0.87 ng/mL and hypercholesterolemia at 2.63 g/L. Ultrasound of the uterus showed polycystic ovaries. The diagnosis of HAIR-AN
syndrome was concluded and the patient was treated.
Conclusion: HAIR-AN syndrome is a rare condition which is characterized by an unusual multisystem disorder in
||Acanthosis nigricans; Hyperandrogenism; HAIR-AN; Insulinin resistance
||1 - 3