Publications Scientifiques

[ Article ] Free radical scavenging and antibacterial potential of two plants extracts (Khaya senegalensis and Pseudocedrela kotschyi) used in veterinary

Date de soumission:	30-04-2018
Année de Publication:	2014
Entité/Laboratoire	Laboratoire d'Etude et de Recherche en Chimie Appliquée (LERCA)
Document type :	Article
Discipline(s) :	Chimie

Titre	Free radical scavenging and antibacterial potential of two plants extracts (Khaya senegalensis and Pseudocedrela kotschyi) used in veterinary
Auteurs	KOUDORO YAYA ALAIN [1], , Dedome O.L. Oronce, [2], Yehouenou Boniface [3], Yovo Mhudro [4], , Agbangnan Dossa C Pascal [4], Tchobo Fidèle Paul [5], , Alitonou Guy Alain [6], AKOEGNINOU AKPOVI [0], Sohounhloue Koko Dominique [0],
Journal:	Elixir International Journal
Catégorie Journal:
Impact factor:	0
Volume Journal:	76
DOI:
Resume	In all developing countries like Benin, medicinal plants were the most widely used especially in rural areas to solve health problems in humans and in animal’s life. But despite this use, all the mysteries of nature were not yet perceived by human. This paper reports the results of the chemical and biological studies of two plants, Khaya senegalensis and Pseudocedrela kotschyi used by farmers in Benin in the treatment of gastro-intestinal diseases in livestock. Throughout the results, we noted in both samples the presence of several secondary metabolites such as saponins, catechic tannins, polyphenols, mucilages, flavonoids, anthocyanins, leuco anthocyanin, reducing compounds, sterols and terpenes. Concerning the extraction yield of metabolites, the binary water-ethanol (50/50) showed the best results compared to each of the two solvents used separately. Concerning the polyphenols content, it varied in the same plant depending of the extraction solvent nature. The test results of the scavenging activity showed a better one with the ethanolic extract of the stem bark of P. kotschyi whereas the stem bark of Khaya senegalensis extracted with semi-ethanol was the most active. Both extracts displayed similar activities (CI50= 4 μg/ml) more pronounced than that of the reference compound used in this study, the BHA (CI50=4.8 μg/mL). The results of antibacterial activity of the ethanolic and hydroethanolic extracts of trunk bark of P. kotschyi had bactericidal activity against Staphylococcus aureus, Salmonella typhi, Escherichia coli and Klebsiella pneumoniae. Concerning K. senegalensis, the ethanolic and hydroethanolic extracts showed an interesting antibacterial activity against Salmonella typhi, Escherichia coli and Klebsiella pneumonia.
Mots clés	Medicinal plants, Secondary metabolites, CI50, Bactericidal
Pages	28720 - 28726
Fichier	(PDF)

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