||Evaluation of iodine intake and status using inductively coupled <1>CrossMark plasma mass spectrometry in urban and rural areas in Benin, West Africa..
Mizéhoun-Adissoda C ,
DESPORT Jean-Claude ,
HOUINATO DISMAND STÉPHANE ,
BIGOT KOFFI ANDRÉ ,
Dalmay François ,
Preux Pierre-Marie ,
Bovet Pascal ,
Moesch Christian ,
||Objecrive: lodine deficiency has severe pathological repercussions. The aim of this study was to
evaluate iodine intake and status in adults in Benin. West Africa.
Methods: We randomly selected 420 participants ages 25 to 64 y and free of visible goiter from
urban and rural settings of South Benin. The participants had a diet based on carbohydrates and
fish. Urine was collected over a 24-h period and samples were assayed for iodine analysis using
inductively coupIed plasma mass spectrometry.
Results: We studied 401 urinary iodine samples. The overall median urinary iodine concentration
(UrC) in 24-h urine was 62.9 !lg/L (interquartile range: 40-96.2 !lg/L). UIC was significantly lower in
women than men (56.5 versus 78.6 !lg/L; P < 0.001) and in rural versus urban areas (54.7 versus
77.8 !lg/L; P < 0.001 ).In multivariate analysis, low urc «100 !lg/L) was positively associated with
women (odds ratio, 2.48; 95% confidence interval, 1.44-4.26; P = 0.001) and body mass index
<25 kg/m2 (odds ratio, 2.06; 95% confidence intervaI. 1.20-3.54; P = 0.008).
Conclusion: lodine intake appeared to be fairly low in the Beninese population, according to World
Health Organization criteria, and factors associated with low iodine intake were identified. Public
health interventions to increase iodine intake, such as iodization of commercial salt and/or fortification
of selected nutrients, should be strengthened at the national leveI.
||560 - 565