Titre |
Phytochemistry and Vasorelaxant activity of some plants used traditionnaly against high blood pressure in Benin |
Auteurs |
TOKOUDAGBA JEAN MARIE [1],
Gandonou Clément [2],
SCHINI-KERTH V. [3],
|
Journal: |
World Journal of Pharmaceutical Sciences |
Catégorie Journal: |
Internationale |
Impact factor: |
0 |
Volume Journal: |
10 |
DOI: |
|
Resume |
The ethnobotanical survey conducted in Zou and Colline regions in February 2015 yielded
twelve plants used traditionally against high blood pressure (hypertension) by the local
population.. The phytochemical analysis and the biological screnning allowed to identify two
plants more active (Carissa eduliss Apocynaceae, Diodiascandess Rubiaceae) than the active
plant identified during a previous biological screnning carried out in 2006 [1]. These two
active plants are very rich in phenolic compounds and have the same phytochemical profile in
contrast to the others plants which have different phytochemical profile. The active plants
have an antioxidant activity closer to that of the standards used. Some plants of the sample
have a very strong antioxidant activity but are not active. The vasorelaxant activity of these
two plants (Carissa edulis Apocynaceae, Diodia scandess Rubiaceae) is superior to the
vasorelexant activity of Parkia biglobosa (Mimosaceae) [1]. Through this study, two new
plants traditionally used against hypertension are retained among the twelve selected plants. |
Mots clés |
Medicinal plants, arterial hypertension, vasorelaxant activity |
Pages |
40 - 48 |
Fichier |
(PDF) |