Titre |
Buruli Ulcer: Epidemiological, Clinical and Biological Profile of Patients in the Centre de Depistage et de Traitement d’Allada (Benin) from 2010 to 2014 |
Auteurs |
DEGBOE BÉRÉNICE [1],
AKPADJAN GBEMAWONMEDE FABRICE [5],
|
Journal: |
Journal of Cosmetics, Dermatological Sciences and Applications |
Catégorie Journal: |
Internationale |
Impact factor: |
0.89 |
Volume Journal: |
9 |
DOI: |
DOI: 10.4236/jcdsa.2019.92006 |
Resume |
Abstract
Introduction: The objective of our work was to describe the epidemiological,
clinical and biological profile of Buruli ulcer in “Centre de Dépistage et de
traitement de l’ulcère de Buruli” (CDTUB) in Allada. Methods: A descriptive
and retrospective study focused on new cases of Buruli ulcer received in the
CDTUB of Allada from 2010 to 2014. The diagnosis of Buruli ulcer was based
on epidemiological, clinical and biological arguments. Results: Over 5 years,
274 new cases of Buruli ulcer have been diagnosed. The average age of the patients
was 12 years and the sex ratio was 0.8. The average time to first consultation
was 45 days. Clinically, 61% had a joint functional limitation. Lesions
were ulcerated in 69% of cases, category I (26%), category II (53%), category
III (21%) and were present on the lower limbs in 57% of cases. Microscopy
was positive in 65.7% of cases and PCR in 78.1% of cases. Microscopy supplemented
by PCR confirmed the diagnosis in 81% of cases. Conclusion: The
epidemiological, clinical and biological profile of Buruli ulcer in Allada was
characterized by a predominant disease in children, a predominance of ulcerated forms and a decisive contribution of PCR to the diagnosis. |
Mots clés |
Buruli Ulcer, Epidemiology, Clinical Profile, Biological Confirmation, Benin |
Pages |
67 - 80 |
Fichier |
(PDF) |