Publications Scientifiques

[ Article ] Contribution of the Dosage of Nt-ProBNP in the Assessment of PulmonaryEmbolismSeverity in Black AfricanCommunity

Date de soumission: 08-01-2017
Année de Publication: 2015
Entité/Laboratoire Unité de Médécine Interne (UMI)
Document type : Article
Discipline(s) : Médécine Générale et interne
Titre Contribution of the Dosage of Nt-ProBNP in the Assessment of PulmonaryEmbolismSeverity in Black AfricanCommunity
Auteurs ZANNOU DJIMON MARCEL [1], AGBODANDE KOUESSI ANTHELME [2], AZON KOUANOU ANGÈLE [3], BAGLO TATIANA [4], WANVOEGBE FINANGNON ARMAND [5], EYISSE YASMINE [6], MOUSSE LATIF [7],
Journal: Internal Medicine: Open Access
Catégorie Journal: Internationale
Impact factor: 0
Volume Journal: 5
DOI: http://dx.doi.org/10.4172/2165-8048.1000184
Resume Objective: To determine the role of NT-proBNP in the assessment of the severity of pulmonary embolism. Patients and methods: The study was performed at Atinkanmey, a private hospital of Cotonou. It is a retrospective, analytical and transversal study, over a period of 3 years (1 January 2009 to 31 December 2011). The study included 35 patients ≤75 years followed for pulmonary embolism with whom the NT-proBNP dosage was performed. NT-proBNP was compared to other severity criteria such as low blood pressure, tachycardia, Pulmonary Embolism Severity Index, the right ventricular trombosis and dilatation of the right cavities associated with PAH. Results: NTproBNP is lower than 1000ng /L in 27 patients (77.1%) and higher than 1000ng/L in 8 patients. The sensitivity of NT-proBNP is low compared to severity criteria studied. It varies from 33% to 50%. The specificity is improved and reached 100% when the NT-proBNP is compared to dilation of the right cavities. The best negative predictive value is obtained with low blood pressure (92.6%). The best positive predictive value (PPV) was found by comparing the NT-proBNP to dilatation of the right cavities. Conclusion: The rise of NTproBNP is not always associated with the presence of gravity criteria studied. Normality seems more associated with lack of dilation of the right cavities.
Mots clés NT-proBNP; Pulmonary embolism; Gravity
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